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FEATURES

FAMILY

isocitrate and isopropylmalate dehydrogenases family

DESCRIPTION

Also known as HICDH_THET2, hicd, hdh, hicdh. Catalyzes the NAD(+)-dependent conversion of homoisocitrate to alpha-ketoadipate. In addition, has high activity with citrate, but is inactive with 3-isopropylmalate. Homotetramer. Dimer of dimers. The homotetramer can transiently dissociate into homodimers.

Also known as HICDH_THET2, hicd, hdh, hicdh. Catalyzes the NAD(+)-dependent conversion of homoisocitrate to alpha-ketoadipate. In addition, has high activity with citrate, but is inactive with 3- ...

EXTERNAL LINKS

uniprot
enzyme classification

hicd

Homoisocitrate dehydrogenase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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