FEATURES

DESCRIPTION

Also known as ERI1_ASHGO, ERI1. Probable component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins. Interacts with GPI2, suggesting that it is a component of the GPI-GnT complex, probably composed of GPI1, GPI2, GPI3, GPI15, and ERI1.

EXTERNAL LINKS

uniprot
enzyme classification

ERI1

Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit

ERI1

Structural Ligandability

Domains Chains

Distribution