FEATURES

FAMILY

DESCRIPTION

Also known as AMGO1_HUMAN, AMIGO1, ALI2, AMIGO, KIAA1163. Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Homodimer, and heterodimer with AMIGO2 and AMIGO3. Interacts with KCNB1.

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EXTERNAL LINKS

AMIGO1

Amphoterin-induced protein 1

ligandability Mutations

AMIGO1

Molecular Synopsis