FEATURES

DESCRIPTION

Also known as LYPD6_HUMAN, LYPD6. Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs (PubMed:27344019). Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity). Interacts with nicotinic acetylcholine receptors (nAChRs) including CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNB2 and CHRNB4 (PubMed:27344019).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LYPD6

Ly6/PLAUR domain-containing protein 6

Mutations

Mutation(s) distribution

Mutations table

Search Mutation