FEATURES

FAMILY

DESCRIPTION

Also known as GALSF_BACTN, BT_3333. Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS) and dermatan sulfate (DS). Catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units (PubMed:25002587). GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract (PubMed:25002587).

EXTERNAL LINKS

uniprot
enzyme classification

BT_3333

N-acetylgalactosamine-6-O-sulfatase

Mutations

Mutation(s) distribution

Mutations table

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