FEATURES

FAMILY

DESCRIPTION

Also known as MIRO_DROME, Miro. Mitochondrial GTPase involved in mitochondrial trafficking (PubMed:16055062, PubMed:16717129, PubMed:22396657). Forms an essential protein complex with Milt that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria (PubMed:16717129). Required for axonal transport to synapses within nerve terminals (PubMed:16055062, PubMed:22396657). Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs) (PubMed:16055062). Interacts with kinesin-associated protein milt.

EXTERNAL LINKS

uniprot
enzyme classification

Miro

Mitochondrial Rho GTPase

Miro

Molecular Synopsis