FEATURES

FAMILY

DESCRIPTION

Also known as RASEF_HUMAN, RASEF, RAB45. Binds predominantly GDP, and also GTP (PubMed:17448446). Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules (PubMed:30814157). Homodimer (PubMed:17448446). Interacts with the dynein-dynactin complex (PubMed:30814157).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RASEF

Ras and EF-hand domain-containing protein

RASEF

Molecular Synopsis