FEATURES

FAMILY

DESCRIPTION

Also known as NNRE_MOUSE, Naxe, Aibp, Apoa1bp. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (By similarity). Homodimer (PubMed:18202122). Interacts with APOA1 and APOA2 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Naxe

Mutations

Mutation(s) distribution

Mutations table