FEATURES

FAMILY

DESCRIPTION

Also known as SESQ1_HUMAN, PHETA1, FAM109A. Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. Forms homodimers and heterodimers with PHETA2 (PubMed:21233288). Interacts with OCRL and INPP5B (PubMed:20133602, PubMed:21233288, PubMed:21666675). Interaction with OCRL may be important for endosomal morphology and function (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PHETA1

Sesquipedalian-1

PHETA1

Molecular Synopsis