FEATURES

FAMILY

PA-phosphatase related phosphoesterase family

DESCRIPTION

Also known as PLPP5_HUMAN, PLPP5, DPPL1, HTPAP, PPAPDC1B. Magnesium-independent phospholipid phosphatase with broad substrate specificity (PubMed:17590538). Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate (PubMed:17590538). Phospholipid phosphatases are involved in both the synthesis of lipids and the generation or degradation of lipid-signaling molecules (PubMed:17590538).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PLPP5

Phospholipid phosphatase 5

PLPP5

Molecular Synopsis