FEATURES

FAMILY

DESCRIPTION

Also known as KI18A_HUMAN, KIF18A. Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. Interacts with CENPE and ESR1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KIF18A

Kinesin-like protein KIF18A

KIF18A

Molecular Synopsis