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FEATURES

FAMILY

5'(3')-deoxyribonucleotidase family

DESCRIPTION

Also known as NT5C_HUMAN, NT5C, DNT1, UMPH2. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. Homodimer.

Also known as NT5C_HUMAN, NT5C, DNT1, UMPH2. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and l ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NT5C

5'(3')-deoxyribonucleotidase, cytosolic type

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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