FEATURES

FAMILY

DESCRIPTION

Also known as ABHD3_HUMAN, ABHD3. Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ABHD3

Phospholipase ABHD3

ABHD3

Molecular Synopsis