FEATURES

FAMILY

DESCRIPTION

Also known as JPH3_HUMAN, JPH3, JP3, TNRC22. Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

JPH3

Junctophilin-3

JPH3

Molecular Synopsis