FEATURES

FAMILY

DESCRIPTION

Also known as ROBO4_HUMAN, ROBO4. Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function (PubMed:30455415). Interacts with SLIT2 and ENAH.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ROBO4

Roundabout homolog 4

ROBO4

Molecular Synopsis