FEATURES

FAMILY

DESCRIPTION

Also known as GPI8_HUMAN, PIGK, GPI8. Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Forms a complex with PIGT, PIGS, PIGU and GAA1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PIGK

GPI-anchor transamidase

PIGK

Molecular Synopsis