FEATURES

DESCRIPTION

Also known as SYAP1_HUMAN, SYAP1. Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation (PubMed:23300339). Interacts (via phosphorylated form and BSD domain) with AKT1; this interaction is enhanced in a mTORC2-mediated manner in response to epidermal growth factor (EGF) stimulation and activates AKT1 (PubMed:23300339).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SYAP1

Synapse-associated protein 1

SYAP1

Molecular Synopsis