FEATURES

FAMILY

DESCRIPTION

Also known as VMI2_HHV8P, ORF K4. Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. Monomer. Interacts with human chomokine receptor CXCR4 (PubMed:25612609).

EXTERNAL LINKS

uniprot
enzyme classification

ORF K4

Viral macrophage inflammatory protein 2

ORF K4

Molecular Synopsis