FEATURES

FAMILY

DESCRIPTION

Also known as CD180_HUMAN, CD180, LY64, RP105. May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). M-shaped tetramer of two CD180-LY86 heterodimers.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CD180

CD180 antigen

CD180

Molecular Synopsis