FEATURES

FAMILY

DESCRIPTION

Also known as SH3G3_HUMAN, SH3GL3, CNSA3, SH3D2C. Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo. Interacts with DYDC1. Interacts with FASLG. Interacts with ATXN2. Interacts with BIN2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SH3GL3

Endophilin-A3

SH3GL3

Molecular Synopsis