FEATURES

FAMILY

short-chain dehydrogenases/reductases (SDR) family

DESCRIPTION

Also known as DHB14_HUMAN, HSD17B14, DHRS10, SDR3, SDR47C1. Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta, 17-beta-diol (in vitro). Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HSD17B14

17-beta-hydroxysteroid dehydrogenase 14

HSD17B14

Molecular Synopsis