FEATURES

FAMILY

DESCRIPTION

Also known as CND3_HUMAN, NCAPG, CAPG, NYMEL3. Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NCAPG

Mutations

Mutation(s) distribution

Mutations table