FEATURES

FAMILY

DESCRIPTION

Also known as DUS26_HUMAN, DUSP26, DUSP24, LDP4, MKP8, NATA1, SKRP3. Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Interacts with HSF4.

Also known as DUS26_HUMAN, DUSP26, DUSP24, LDP4, MKP8, NATA1, SKRP3. Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-bindin ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DUSP26

Dual specificity protein phosphatase 26

DUSP26

Molecular Synopsis