FEATURES

DESCRIPTION

Also known as PIP30_HUMAN, PSME3IP1, C16orf94, FAM192A, NIP30, PIP30. Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus. Interacts (via C-terminus) with both free and 20S proteasome-bound forms of the proteasome activator complex subunit PSME3; the interaction is direct.

Also known as PIP30_HUMAN, PSME3IP1, C16orf94, FAM192A, NIP30, PIP30. Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PSME3IP1

PSME3-interacting protein

PSME3IP1

Molecular Synopsis