FEATURES

FAMILY

DESCRIPTION

Also known as RB33B_HUMAN, RAB33B. Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation. Interacts with ATG16L1 (PubMed:21808068). Interaction with ATG16L1 is important for autophagosome formation (By similarity). Interacts with ATG16L2; however interaction is approximately hundred times lower than for ATG16L1 (By similarity). Interacts with RIC1 (via C-terminus domain); the interaction is direct with a preference for RAB33B-GTP (PubMed:23091056). Interacts with RGP1 (PubMed:23091056).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAB33B

Mutations

Mutation(s) distribution

Mutations table