FEATURES

FAMILY

DESCRIPTION

Also known as BOLA2_HUMAN, BOLA2, BOLA2B, BOLA2A. Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts together with the monothiol glutaredoxin GLRX3 (PubMed:26613676, PubMed:27519415). Interacts with GLRX3; forms a heterotrimeric complex composed by two BOLA2 molecules and one GLRX3 molecule; linked by [2Fe-2S] clusters (PubMed:22309771, PubMed:26613676, PubMed:27519415).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BOLA2, BOLA2B

BolA-like protein 2

BOLA2, BOLA2B

Molecular Synopsis