FEATURES

FAMILY

DESCRIPTION

Also known as PKRI1_HUMAN, PRKRIP1. Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:30705154). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity). Component of the pre-catalytic and post-catalytic spliceosome complexes (PubMed:28502770, PubMed:30705154). Interacts with EIF2AK2 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PRKRIP1

PRKR-interacting protein 1

Mutations

Mutation(s) distribution

Mutations table

Search Mutation