FEATURES

FAMILY

DESCRIPTION

Also known as S61A2_HUMAN, SEC61A2. Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity). Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SEC61A2

Protein transport protein Sec61 subunit alpha isoform 2

SEC61A2

Molecular Synopsis