FEATURES

DESCRIPTION

Also known as SPON1_HUMAN, SPON1, KIAA0762, VSGP. Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell. Binds to the central extracellular domain of APP and inhibits beta-secretase cleavage of APP.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SPON1

Spondin-1

SPON1

Molecular Synopsis