FEATURES

FAMILY

DESCRIPTION

Also known as TRPM3_HUMAN, TRPM3, KIAA1616, LTRPC3. Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. In addition, forms heteromultimeric ion channels with TRPM1 which are permeable for calcium and zinc ions (PubMed:21278253). Interacts with TRPM1; the interaction results in the formation of a heteromultimeric cation channel complex.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TRPM3

Transient receptor potential cation channel subfamily M member 3

TRPM3

Molecular Synopsis