FEATURES

FAMILY

DESCRIPTION

Also known as TRPC7_HUMAN, TRPC7, TRP7. Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. Interacts with MX1 and RNF24. Interacts (via ANK-repeat domains) with PRKG1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TRPC7

Short transient receptor potential channel 7

TRPC7

Molecular Synopsis