FEATURES

FAMILY

DESCRIPTION

Also known as VGR1A_PSEAE, vgrG1a. Part of the H1 type VI secretion system (H1-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection (PubMed:21325275, PubMed:24794869). Forms the spike at the tip of the elongating tube formed by haemolysin co-regulated protein 1/Hcp1 (PubMed:26894531). Allows the delivery of the Tse6 toxin to target cells where it exerts its toxicity (PubMed:30177742). Forms homotrimers (PubMed:21325275). Part of the type VI secretion system (T6SS) (PubMed:26894531). Interacts with EagT6 and Tse6; these interactions are required for Tse6 loading onto VgrG1 (PubMed:30177742). Interacts with Hcp1 (PubMed:21325275).

EXTERNAL LINKS

vgrG1a

Type VI secretion system spike protein VgrG1a

vgrG1a

Molecular Synopsis