FEATURES

FAMILY

DESCRIPTION

Also known as AB25B_ARATH, ABCB25, ATM3, STA1. Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not required for mitochondrial and plastid Fe-S enzymes. Probably involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol. Mediates glutathione-dependent resistance to heavy metals such as cadmium and lead, as well as their transport from roots to leaves. Regulates nonprotein thiols (NPSH) and the cellular level of glutathione (GSH). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

ABCB25

ABC transporter B family member 25, mitochondrial

ABCB25

Molecular Synopsis