FEATURES

FAMILY

fibroblast growth factor-binding protein family

DESCRIPTION

Also known as FGFP1_BOVIN, FGFBP1, FGFBP. Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth (By similarity). Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGF1, FGF7, FGF10, FGF22 and HSPG2 (By similarity). Interacts with FGF2.

EXTERNAL LINKS

uniprot
enzyme classification

FGFBP1

Fibroblast growth factor-binding protein 1

FGFBP1

Structural Ligandability

Domains Chains

Distribution