FEATURES

FAMILY

DESCRIPTION

Also known as ENPL_LEIIN, LPG3, GRP94. Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Required for the synthesis of lipophosphoglycan (LPG), a cell surface glycoconjugate (By similarity). Necessary for the attachment of the galactosyl residue to the mannose within the phosphoglycan repeats of the nascent LPG chain (By similarity). Also required for addition of phosphoglycan to acid phosphatase (By similarity). Not required for normal growth (By similarity). Has ATPase activity (PubMed:29568220). Binds heparin with micromolar affinity which may facilitate infection of host cells (PubMed:29568220). Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification

LPG3

Endoplasmin homolog

LPG3

Molecular Synopsis