FEATURES

DESCRIPTION

Also known as SH22A_HUMAN, SH2D2A, SCAP, TSAD, VRAP. Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation. Interacts with KDR. Interacts with TXK and ITK (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SH2D2A

SH2 domain-containing protein 2A

SH2D2A

Molecular Synopsis