FEATURES

FAMILY

DESCRIPTION

Also known as M1IP1_HUMAN, MID1IP1, MIG12. Plays a role in the regulation of lipogenesis in liver. Up-regulates ACACA enzyme activity. Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid. Involved in stabilization of microtubules (By similarity). Homodimer in the absence of THRSP. Heterodimer with THRSP. The homodimer interacts with ACACA and ACACB. Promotes polymerization of Acetyl-CoA carboxylase to form complexes that contain MID1IP1 and ACACA and/or ACACB. Interaction with THRSP interferes with ACACA binding (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MID1IP1

Mid1-interacting protein 1

MID1IP1

Molecular Synopsis