FEATURES

FAMILY

mitochondrion-specific ribosomal protein mL40 family

DESCRIPTION

Also known as RM40_HUMAN, MRPL40, NLVCF, URIM. Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:28892042, PubMed:25838379, PubMed:25278503). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins. mL40 binds to the major groove of the anticodon stem of mt-tRNA(Val) in the central protuberance.

Also known as RM40_HUMAN, MRPL40, NLVCF, URIM. Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:28892042, PubMed:25838379, PubMed:25278503). Mature mammalian 55S mitochond ...

EXTERNAL LINKS

MRPL40

Mutations

Mutation(s) distribution

Mutations table