FEATURES

FAMILY

DESCRIPTION

Also known as ASH1L_HUMAN, ASH1L, KIAA1420, KMT2H. Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3 (PubMed:21239497). Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (By similarity). The physiological significance of the H3K9me1 activity is unclear (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ASH1L

Histone-lysine N-methyltransferase ASH1L

ASH1L

Molecular Synopsis