FEATURES

FAMILY

DESCRIPTION

Also known as IMPA3_HUMAN, BPNT2, IMPA3, IMPAD1. Exhibits 3'-nucleotidase activity toward adenosine 3', 5'-bisphosphate (PAP), namely hydrolyzes adenosine 3', 5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3', 5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1, 4)P2, I(1, 3, 4)P3, I(1, 4, 5)P3 and I(1, 3, 4, 5)P4.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BPNT2

Golgi-resident adenosine 3', 5'-bisphosphate 3'-phosphatase

BPNT2

Molecular Synopsis