FEATURES

FAMILY

DESCRIPTION

Also known as PHB1_SCHPO, phb1. Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Has an antiproliferative activity. Regulates replicative life span (By similarity). The mitochondrial prohibitin complex consists of two subunits (PHB1 and PHB2), assembled into a membrane-associated ring-shaped supercomplex of approximately 1 mDa.

EXTERNAL LINKS

uniprot
enzyme classification

phb1

Prohibitin-1

phb1

Structural Ligandability

Domains Chains

Distribution