FEATURES

FAMILY

DESCRIPTION

Also known as B4GT6_HUMAN, B4GALT6. Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:3099851, PubMed:1551920, PubMed:24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

B4GALT6

Beta-1, 4-galactosyltransferase 6

B4GALT6

Molecular Synopsis