FEATURES

DESCRIPTION

Also known as MARCO_HUMAN, MARCO, SCARA2. Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (PubMed:12847263). Homotrimer; disulfide-linked. Trimers may assemble in larger oligomers thus resulting in the creation of a large surface capable of interacting with very large ligands.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MARCO

Macrophage receptor MARCO

MARCO

Molecular Synopsis