FEATURES

FAMILY

DESCRIPTION

Also known as SRP68_HUMAN, SRP68. Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRP68

Mutations

Mutation(s) distribution

Mutations table