FEATURES

DESCRIPTION

Also known as ZN346_HUMAN, ZNF346, JAZ. Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053). May bind to specific miRNA hairpins (PubMed:28431233). Forms a heteromeric complex with XPO5 and ILF3. Found in a nuclear export complex with XPO5, RAN, ILF3, ZNF346 and double-stranded RNA. Interacts with XPO5. Interacts with ILF3 in an RNA-independent manner.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ZNF346

Zinc finger protein 346

ZNF346

Molecular Synopsis