FEATURES

FAMILY

DESCRIPTION

Also known as SRPK3_HUMAN, SRPK3, MSSK1, STK23. Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRPK3

SRSF protein kinase 3

SRPK3

Molecular Synopsis