FEATURES

FAMILY

DESCRIPTION

Also known as TRMI_PYRAB, trmI, pimT-like. Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence. Homotetramer composed of a dimer of dimers; disulfide-linked. Disulfide bonds are important for the stability of TrmI at extreme temperatures.

EXTERNAL LINKS

uniprot
enzyme classification

trmI

tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI

Mutations

Mutation(s) distribution

Mutations table

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