FEATURES

FAMILY

DESCRIPTION

Also known as MSPS_DROME, msps. Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. May act as a microtubule antipause factor that rapidly catalyzes the transition from pause to either growth or shrinkage. Involved in mitotic spindle elongation. Involved in the establishment of cell polarity and mitotic spindle orientation in neuroblasts. Required for maintaining the bipolarity of acentrosomal meiotic spindles; the function is dependent on tacc and involves ncd. Involved in oocyte microtubule cytoskeleton organization and bicoid mRNA localization. Seems to be involved in elongation of kinetochore-derived microtubule fibers. Interacts with tacc, dgt6 (PubMed:11433295, PubMed:19836241). Interacts with mv (PubMed:33725482).

EXTERNAL LINKS

msps

Protein mini spindles

msps

Molecular Synopsis