FEATURES

FAMILY

DESCRIPTION

Also known as TRPV2_RAT, Trpv2, Sac2b, Vrl1. Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH (By similarity). Homotetramer (Probable). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3. Interacts with SLC50A1; the interaction probably occurs intracellularly and depends on TRPV2 N-glycosylation.

Also known as TRPV2_RAT, Trpv2, Sac2b, Vrl1. Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1 ...

EXTERNAL LINKS

Trpv2

Transient receptor potential cation channel subfamily V member 2

Trpv2

Molecular Synopsis