FEATURES

FAMILY

monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

DESCRIPTION

Also known as SL9A8_HUMAN, SLC9A8, KIAA0939, NHE8. Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC9A8

Sodium/hydrogen exchanger 8

SLC9A8

Molecular Synopsis